Table 3.

CAU (SNP + GROUP) MODELS. SIGNIFICANT SNPs. CAUCASIAN.

									ADDITIVE				DOMINANT				RECESSIVE				HETHOM
									ADD				DOM				REC				HOM				HET
CHROM	LOCUS	POS	ID	REF	ALT	A1	A1_FREQ	OBS_CT	OR_CI95	pvalue	qvalue	lfdr	OR_CI95	pvalue	qvalue	lfdr	OR_CI95	pvalue	qvalue	lfdr	OR_CI95	pvalue	qvalue	lfdr	OR_CI95	pvalue	qvalue	lfdr
1	LYPLAL1	219527177	rs2785980	T	C	C	0.326	1101	0.79 (0.62-1.01)	0.062	0.037	0.224	0.74 (0.54-1.02)	0.064	0.036	0.231	0.74 (0.42-1.31)	0.308	0.219	0.997	0.65 (0.36-1.18)	0.161	0.196	0.865	0.76 (0.55-1.06)	0.110	0.141	0.714
1	MTR	236885200	rs1805087	A	G	G	0.180	1102	0.73 (0.53-1.00)	0.050	0.030	0.169	0.75 (0.53-1.06)	0.098	0.054	0.383	0.31 (0.08-1.22)	0.095	0.081	0.512	0.29 (0.07-1.24)	0.096	0.125	0.645	0.79 (0.56-1.13)	0.205	0.235	0.926
2	DPYSL5	26930006	rs1371614	C	T	T	0.260	1102	1.21 (0.95-1.54)	0.132	0.076	0.488	1.53 (1.12-2.10)	0.008	0.006	0.020	0.59 (0.29-1.20)	0.145	0.118	0.744	0.75 (0.36-1.57)	0.448	0.385	0.981	1.70 (1.23-2.35)	0.001	0.015	0.014
2	GCKR	27518370	rs780094	T	C	T	0.472	1104	0.74 (0.59-0.92)	0.007	0.006	0.019	0.67 (0.48-0.93)	0.016	0.010	0.042	0.66 (0.44-0.99)	0.042	0.037	0.196	0.54 (0.35-0.86)	0.009	0.015	0.051	0.73 (0.51-1.04)	0.080	0.107	0.549
2	COBLL1	164694691	rs7607980	T	C	C	0.144	1102	0.67 (0.47-0.95)	0.023	0.014	0.066	0.63 (0.43-0.92)	0.016	0.010	0.041	0.73 (0.24-2.28)	0.594	0.344	1.000	0.66 (0.20-2.15)	0.489	0.406	0.981	0.62 (0.42-0.93)	0.020	0.029	0.117
3	IGF2BP2	185793899	rs4402960	G	T	T	0.315	1104	1.54 (1.21-1.95)	0.000	0.006	0.004	1.66 (1.20-2.30)	0.002	0.006	0.008	1.89 (1.18-3.04)	0.008	0.008	0.033	2.37 (1.42-3.95)	0.001	0.015	0.012	1.53 (1.09-2.15)	0.015	0.022	0.085
3	IGF2BP2	185795604	rs7651090	A	G	G	0.315	1104	1.52 (1.20-1.94)	0.001	0.006	0.004	1.67 (1.20-2.31)	0.002	0.006	0.008	1.79 (1.10-2.92)	0.020	0.018	0.078	2.27 (1.34-3.85)	0.002	0.015	0.019	1.56 (1.11-2.19)	0.011	0.016	0.062
5	ZBED3	77130042	rs7708285	G	A	G	0.298	1104	1.24 (0.98-1.57)	0.078	0.046	0.292	1.24 (0.90-1.70)	0.180	0.097	0.623	1.52 (0.92-2.50)	0.099	0.084	0.536	1.63 (0.97-2.76)	0.066	0.090	0.460	1.16 (0.83-1.62)	0.376	0.361	0.979
9	GLIS3	4287466	rs7041847	A	G	G	0.470	1101	0.87 (0.69-1.09)	0.228	0.119	0.663	0.71 (0.51-1.00)	0.048	0.028	0.156	1.02 (0.70-1.49)	0.924	0.444	1.000	0.80 (0.52-1.23)	0.311	0.316	0.973	0.67 (0.47-0.97)	0.033	0.047	0.210
9	GLIS3	4289050	rs7034200	C	A	C	0.495	1103	0.90 (0.72-1.13)	0.363	0.169	0.769	0.68 (0.49-0.96)	0.030	0.018	0.086	1.14 (0.80-1.62)	0.485	0.300	1.000	0.84 (0.55-1.27)	0.401	0.368	0.980	0.61 (0.42-0.89)	0.010	0.016	0.059
9	GLIS3	4293150	rs10814916	A	C	A	0.475	1097	0.87 (0.70-1.10)	0.244	0.126	0.681	0.67 (0.48-0.94)	0.021	0.013	0.055	1.10 (0.76-1.59)	0.621	0.346	1.000	0.81 (0.53-1.24)	0.335	0.331	0.976	0.61 (0.43-0.89)	0.009	0.015	0.053
9	SARDH	133734024	rs573904	C	T	T	0.284	1103	1.20 (0.94-1.53)	0.140	0.081	0.512	1.32 (0.96-1.81)	0.083	0.047	0.318	1.08 (0.62-1.90)	0.786	0.392	1.000	1.24 (0.69-2.24)	0.475	0.400	0.981	1.34 (0.96-1.86)	0.084	0.111	0.574
11	KCNJ11	17387083	rs5215	C	T	C	0.351	1100	1.24 (0.98-1.56)	0.071	0.042	0.262	1.45 (1.04-2.01)	0.027	0.016	0.073	1.09 (0.68-1.75)	0.722	0.372	1.000	1.35 (0.81-2.26)	0.251	0.282	0.956	1.48 (1.05-2.08)	0.026	0.038	0.158
11	MTNR1B	92940662	rs1387153	C	T	T	0.293	1103	1.49 (1.17-1.89)	0.001	0.006	0.006	1.63 (1.18-2.24)	0.003	0.006	0.009	1.71 (1.02-2.85)	0.040	0.036	0.185	2.12 (1.23-3.65)	0.007	0.015	0.041	1.54 (1.10-2.16)	0.011	0.017	0.065
11	MTNR1B	92965261	rs10830962	C	G	G	0.426	1098	1.31 (1.05-1.64)	0.019	0.012	0.053	1.55 (1.08-2.21)	0.017	0.010	0.042	1.31 (0.88-1.93)	0.182	0.144	0.854	1.69 (1.06-2.69)	0.028	0.040	0.172	1.50 (1.03-2.18)	0.036	0.050	0.232
11	MTNR1B	92975544	rs10830963	C	G	G	0.275	1102	1.51 (1.19-1.91)	0.001	0.006	0.005	1.73 (1.26-2.37)	0.001	0.006	0.004	1.60 (0.96-2.67)	0.072	0.063	0.378	2.04 (1.18-3.51)	0.010	0.016	0.060	1.67 (1.20-2.33)	0.003	0.015	0.021
13	PDX1	27917061	rs2293941	G	A	A	0.242	1102	1.20 (0.93-1.54)	0.154	0.086	0.545	1.36 (0.99-1.87)	0.055	0.031	0.187	0.90 (0.46-1.75)	0.750	0.382	1.000	1.04 (0.52-2.05)	0.920	0.542	0.982	1.42 (1.03-1.97)	0.035	0.049	0.222
14	WARS	100372924	rs3783347	G	T	T	0.173	1104	0.73 (0.53-1.01)	0.057	0.034	0.200	0.68 (0.47-0.97)	0.032	0.018	0.091	0.99 (0.37-2.63)	0.981	0.455	1.000	0.88 (0.33-2.36)	0.802	0.507	0.982	0.66 (0.45-0.95)	0.027	0.040	0.168
17	GLP2R	9888058	rs17676067	T	C	C	0.271	1103	1.30 (1.02-1.65)	0.035	0.022	0.110	1.27 (0.92-1.74)	0.140	0.077	0.533	1.80 (1.07-3.01)	0.027	0.024	0.111	1.92 (1.12-3.29)	0.018	0.027	0.107	1.16 (0.83-1.62)	0.396	0.368	0.980
20	FOXA2	22578963	rs6048205	A	G	G	0.050	1104	0.47 (0.24-0.90)	0.023	0.014	0.065	0.47 (0.24-0.91)	0.026	0.016	0.072	0.50 (0.02-13.38)	0.682	0.362	1.000	0.48 (0.02-12.67)	0.658	0.456	0.982	0.51 (0.26-0.99)	0.045	0.063	0.301
20	SLC17A9	62967547	rs3746750	A	G	A	0.345	1100	0.73 (0.57-0.94)	0.015	0.009	0.039	0.65 (0.47-0.89)	0.008	0.006	0.019	0.78 (0.45-1.34)	0.369	0.255	1.000	0.63 (0.36-1.11)	0.109	0.140	0.706	0.65 (0.47-0.91)	0.012	0.019	0.071

Table that summarizes the most relevant results of the analysis of SNPs + Group models in Caucasian (CAU) ethnicity. ADD, Additive model; DOM, dominant model; REC, recessive model; HETHOM, heterozygous-homozygous model; CHROM, Chromosome code; LOCUS, Locus/Gene; POS, Base-pair coordinate [GRCh38]; ID, Variant ID; REF, Reference allele; ALT, Alternate allele; A1, Counted allele in logistic regression; A1_FREQ, minor allele frequency; OBS_CT, Number of samples in the regression; OR_CI95, odds ratio with 95% confidence interval.