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. 2022 Oct 13;13:1037115. doi: 10.3389/fimmu.2022.1037115

Table 2.

Correlation analysis of CC16 with clinical measures and immunological serum markers in n = 16 patients treated for SARS-CoV-2 infection.

SARS-CoV-2 infection rS p-value
subjects, n (%) 16 (100)
time since diagnosis, days 31 (15; 38) 0.797 3.69 x 10-4
WHO clinical progression scale, 0-10 7 (5; 7) 0.312 0.24
age, years 54.44 ± 19.93 0.423 0.10
CRP, ng/ml 77.02 ± 62.96 -0.024 0.93
IL-6, pg/ml 43.05 (19.55; 61.65) 0.196 0.48
D-dimer, ng/ml 2.85 (1.66; 5.83) 0.302 0.32
platelets, 109/L 220 (126.5; 303.2) -0.625 9.56 x 10-3
leucocytes, 109/L 9.74 (6.14; 15.9) -0.191 0.48
lymphocytes, 109/L 1.1 (1.04; 1.15) -0.300 0.68
granulocytes, 109/L 7.12 (6.25; 14.9) 0.300 0.68
GOT, U/l 95.9 (54.95; 199.03) -0.132 0.62
GGT, U/l 336.5 (172.8; 596.8) -0.104 0.70
creatinine, µmol/l 110 (51.25; 157.5) 0.471 0.07

Data was tested for normal distribution using Shapiro-wilk test. Normally distributed data are presented as mean ± standard deviation, non-normally distributed data as median (25th, 75th percentile). Categorical variables are presented as number of subjects (percentages). Statistical significance was tested using Spearman’s rank correlation tests. CRP, C-reactive protein; IL-6, interleukin-6, GOT, glutamate oxaloacetate transaminase, GGT, gamma-glutamyltransferase.