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Toxicity parameter of selected chemicals.
| Toxicity parameter | Metabolites name | |||
|---|---|---|---|---|
| Avicularin | Asiatic acid | Curcumin | Guaijaverin | |
| AMES toxicity | No | No | No | No |
| Max. Tolerated dose (log mg/kg/day) | 0.576 | 0.078 | 0.081 | 0.494 |
| hERG I inhibitor | No | No | No | No |
| hERG II inhibitors | No | No | No | Yes |
| Oral rat acute toxicity, LD50 (mol/kg) | 2.543 | 2.592 | 1.833 | 2.585 |
| Hepatotoxicity | No | No | No | No |
| Skin sensitisation | No | No | No | No |
| Minnow toxicity (log mM) | 6.668 | 1.106 | −0.081 | 5.071 |
