Table 2.

Transitions in LN classification (ISN/RPS 2003) from the first to the second biopsy

LN class at first (baseline) biopsy, (N = 56)	LN class at second biopsy (n = 56)a
	II	III	IV	V	Mixed	VI	Indeterminate	Normal histologyc	Transitionb, n (%)
II (n = 1)	1	0	0	0	0	0	0	0	0
III (n = 13)a,c	2	6	2	0	0	0	1a	2	4 (7.1)
IV (n = 36)c	4	16	10	2	1	1	0	2	10 (17.9)
V (n = 5)	0	0	0	4	1	0	0	0	1 (1.8)
Mixed (n = 1)	0	0	0	0	1	0	0	0	0
Totalc	7	22	12	6	3	1	1	4	15 (26.8)

^aThe histological class of LN at the second biopsy could not be accurately determined in one patient with class III at baseline biopsy.

^bTransition from non-proliferative (class II) to proliferative (class III or IV) or membranous (class V) or mixed, transition from proliferative (class III or IV) to non-proliferative (class II) or membranous (class V) or mixed and transition from membranous (class V) to non-proliferative (class II) or proliferative (class III or IV) or mixed.

^cThe renal histology was normal in the second biopsy in four patients (two with class III and two with class IV at the first biopsy).

The numbers in bold represent the number of biopsies that maintain the same histological class.