Table 1.
Baseline characteristics of patients after first kidney graft failure depending on kidney replacement therapy
| Variable | Total (n = 2045) | HD (n = 1829) | PD (n = 168) | TX (n = 48) | P-value | Missing (%) |
|---|---|---|---|---|---|---|
| Gender (n, %) | ||||||
| Male | 1244 (60.8) | 1122 (61.3) | 93 (55.4) | 29 (60.4) | ||
| Female | 801 (39.2) | 707 (38.7) | 75 (44.6) | 19 (39.6) | .314 | 0 |
| Age at first TX (n, %) | ||||||
| 0–44 years | 737 (36.0) | 636 (34.8) | 81 (48.2) | 20 (41.7) | ||
| 45–64 years | 932 (45.6) | 837 (45.8) | 74 (44.0) | 21 (43.7) | ||
| >65 years | 376 (18.4) | 356 (19.4) | 13 (7.8) | 7 (14.6) | <.001 | 0 |
| Age at first TX | ||||||
| Years (SD) | 46.0 (16.5) | 49.7 (16.2) | 43.0 (16.5) | 43.7 (19.8) | <.001 | 0 |
| Diabetes | ||||||
| No | 1412 (69.0) | 1241 (67.9) | 137 (81.5) | 34 (70.8) | ||
| Yes | 633 (31.0 | 588 (32.1) | 31 (18.5) | 14 (29.2) | .001 | 0 |
| Cardiovascular disease (n, %) | ||||||
| No | 988 (48.9) | 851 (47.1) | 109 (65.2) | 28 (62.2) | ||
| Yes | 1030 (51.1) | 955 (52.9) | 58 (34.8) | 17 (37.8) | <.001 | 1 |
| First TX type (n, %) | ||||||
| Deceased | 1919 (93.8) | 1719 (94.0) | 158 (94.0) | 42 (87.5) | ||
| Live | 126 (6.2) | 110 (6.0) | 10 (6.0) | 6 (12.5) | .181 | 0 |
| %PRA (n, %) | ||||||
| 0–10% | 1666 (95.4) | 1500 (95.5) | 127 (93.4) | 29 (93.5) | ||
| 11–50% | 66 (3.8) | 57 (3.7) | 7 (5.1) | 2 (6.5) | ||
| >50% | 15 (0.8) | 13 (0.8) | 2 (1.5) | 0 (0) | .548 | 15 |
| Cause of first TX failure (n, %) | ||||||
| PNF | 60 (3.4) | 59 (3.7) | 1 (0.7) | 0 (0) | ||
| Surgical complications | 199 (11.1) | 176 (10.9) | 16 (10.5) | 7 (33.3) | ||
| Chronic damage | 1177 (65.9) | 1062 (65.8) | 102 (67.1) | 13 (61.9) | ||
| Acute rejection | 102 (5.7) | 93 (5.8) | 9 (5.9) | 0 (0) | ||
| Other | 249 (13.9) | 224 (13.8) | 24 (15.8) | 1 (4.8) | .084 | 13 |
| First TX survival | ||||||
| (median month, P25-P75) | 81 (23–148) | 83 (23–147) | 86 (37–155) | 58 (12–159) | .359 | 0 |
| Age at first graft failure | ||||||
| Years (SD) | 56.9 (15.1) | 57.6 (14.9) | 51.5 (15.6) | 51.9 (18.2) | <.001 | 0 |
| Functional autonomy (n, %) | ||||||
| Normal/nearly normal | 1357 (80.9) | 1212 (79.8) | 127 (92.0) | 18 (85.7) | ||
| Limited | 244 (14.6) | 232 (15.3) | 10 (7.2) | 2 (9.5) | ||
| Dependent/hospitalized | 76 (4.5) | 74 (4.9) | 1 (0.8) | 1 (4.8) | .004 | 18 |
HD, haemodialysis; PD, peritoneal dialysis; PNF, primary non function; PRA, panel reactive antibody; SD, standard deviation; TX, transplant.