Table 1.
Characteristics of participants who underwent total hip arthroplasty.
| Variable | THA cohort | CH (VAF ≥ 1%) | Non-CH | non-adjusted p (CH vs. non-CH) |
|---|---|---|---|---|
| n (%) | 261 | 127 (48.7) | 134 (51.3) | |
| Center | 0.20 | |||
| TUM, n (%) | 177 (68) | 91 (51) | 86 (49) | |
| TUD/UHL, n (%) | 84 (32) | 36 (43) | 48 (57) | |
| Age [years], median (range) | 70 (18–86) | 72 (53–86) | 68 (18–83) | <0.001 |
| Male sex, n (%) | 93 (36) | 39 (30) | 54 (40) | 0.11 |
| Blood counts | ||||
| Leukocytes [109/l], median (range) | 6.7 (3.6–11.7) | 6.8 (4.0–11.6) | 6.7 (3.6–11.7) | 0.37 |
| Hemoglobin [g/dl], median (range) | 13.4 (8.0–18.4) | 12.7 (8.0–16.9) | 13.7 (8.0–18.4) | 0.003 |
| MCV [fL], median (range) | 90.0 (80.0–102.9) | 92.0 (82.0–102.0) | 89.0 (80.0–102.9) | 0.021 |
| Platelets [109/l], median (range) | 275 (110–563) | 275 (110–563) | 274 (144–490) | 0.70 |
Clinical characteristics were compared between groups using the chi-square test for categorical variables and the Wilcoxon–Mann–Whitney test for continuous variables.
CH clonal hematopoiesis, MCV mean corpuscular volume, TUM Technical University Munich, TUD Technical University Dresden, UHL University Hospital Leipzig, THA total hip arthroplasty, VAF variant allele frequency.