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. 2022 Aug 29;36(11):2678–2689. doi: 10.1038/s41375-022-01686-y

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Fig. 4 — A GSEA example of BMSC from tMN vs. other MN shows enrichment of metabolic pathways. The normalized enrichment score (NES), P values and false discovery rate (FDR) are given; B comparison of mitochondrial ATP (mitoATP) production rate and glycolytic ATP (glycoATP) production rate between Healthy (n = 3) and tMN BMSC (n = 5). Data were expressed relative to the total DNA. Effect of glycolysis inhibitor 2DG on mitochondrial and glycolytic production rate in C Healthy BMSC (n = 3) and D tMN BMSC (n = 3). All bars indicate mean, and all error bars indicate SD. Mann–Whitney test was used to detect statistically significant differences between cohorts. Asterisks display P values **P < 0.01, ****P < 0.001.