Table 2:
Summary of diagnostic performance of miRNA-based biomarker panel in the training and validation cohorts.
| Training cohort (%, CI) | Validation cohort (%, CI) | |
|---|---|---|
| AUC | 0.92 (0.85-0.96) | 0.88 (0.82-0.93) |
| Accuracy | 0.86 (0.79-0.92) | 0.84 (0.77-0.89) |
| Sensitivity | 0.90 (0.81-0.96) | 0.82 (0.71-0.90) |
| Specificity | 0.80 (0.65-0.90) | 0.86 (0.75-0.94) |
| PPV | 0.88 (0.78-0.94) | 0.88 (0.78-0.94) |
| NPV | 0.84 (0.69-0.93) | 0.80 (0.69-0.89) |
AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value