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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Gastroenterology. 2022 Jul 16;163(5):1252–1266.e2. doi: 10.1053/j.gastro.2022.06.090

Figure 2.

Figure 2.

Performance evaluation of cell-free and exosomal miRNA biomarker panel in clinical cohorts by qRT-PCR. Representative heatmap of statistically significant and upregulated candidate (A) cf-miRNAs and (B) exo-miRNAs in patients with PDAC versus non-disease controls. (C) ROC curves analysis for the cf-miRNA, exo-miRNA or cf- and exocombination panel in the training cohort. (D) ROC curves analysis for the cf-miRNA, exo-miRNA and cf and exosomal combination panels in the validation cohort. [Exo: exosomal; miRNA: micro RNA; qRT-PCR: Quantitative Reverse transcription polymerase chain reaction; cf: cell-free; AUC: Area under the curve; ROC: receiver operating characteristic]