Table 1.
Candidate genes with different expressions in brain metastasis patients with SCLC. p-value ≤ 0.05.
| Up-regulate genes | logFC | P-value | Down-regulate genes | logFC | P-value |
|---|---|---|---|---|---|
| PRSS33 | 3.383007303 | 0.004560695 | OCLN | − 3.566468452 | 0.022160353 |
| WHAMMP2 | 2.99733975 | 0.005815325 | XLOC_l2_007062 | − 3.329664096 | 0.013558958 |
| XLOC_l2_000941 | 2.687330175 | 4.1957237415278E-05 | ZIM2 | − 2.854825242 | 0.028619212 |
| MYOM2 | 2.601569126 | 0.021263756 | PNMA2 | − 2.660709775 | 0.01010599 |
| C1orf87 | 2.59361413 | 1.62961553882741E-05 | MPO | − 2.603630721 | 0.034713463 |
| PIGC | 2.568682566 | 0.04592453 | ANKRD34B | − 2.435841569 | 0.049785848 |
| C1orf105 | 2.537416642 | 0.004661527 | ABCA13 | − 2.425532635 | 0.010254371 |
| ALOX15 | 2.372469038 | 0.006367303 | LOC646627 | − 2.409993098 | 0.037554779 |
| IGIP | 2.276075691 | 0.000645279 | SLC14A1 | − 2.380643274 | 0.001828896 |
| SPAG6 | 2.242164253 | 0.025026256 | ITLN1 | − 2.341855873 | 0.003294184 |
| LPAR3 | 2.233936235 | 0.019032771 | CRB1 | − 2.310587746 | 0.014682181 |
| ZNF416 | 2.102556319 | 0.000160004 | PGK2.00 | − 2.111562308 | 0.019712849 |
| EMR4P | 2.088110399 | 0.006628096 | KRT1 | − 2.043848253 | 0.023066534 |
| TRIP13 | 2.06727697 | 0.000330399 | SLC2A5 | − 1.999212172 | 0.031409788 |
| IL5RA | 2.061453481 | 0.006381159 | PGLYRP1 | − 1.943771474 | 0.032295719 |
| TM4SF19 | 2.012294101 | 0.005361822 | FAM83A | − 1.926935845 | 0.002982599 |
| PCDHGA9 | 2.009416266 | 0.00140228 | XK | − 1.915279305 | 0.008257932 |
| PIGW | 1.995038208 | 0.038464331 | DPCD | − 1.83374777 | 0.040212628 |
| ZNF599 | 1.985801014 | 0.001438597 | AMFR | − 1.828192394 | 0.000293755 |
| LGSN | 1.972203834 | 0.006590149 | TMEM158 | − 1.802895011 | 0.001143757 |
| TMEM176B | 1.953156305 | 0.023746468 | DACH2 | − 1.800987665 | 0.00095326 |
| TMEM176A | 1.935063753 | 0.030140607 | OSBP2 | − 1.790583828 | 0.044198947 |
| TTC39B | 1.907722674 | 0.014295311 | CRAT | − 1.788273793 | 0.012034785 |
| SIGLEC8 | 1.861465376 | 0.004428622 | ZNF608 | − 1.78743558 | 0.002590702 |
| PRAMEF20 | 1.856405961 | 0.02697871 | CYBRD1 | − 1.776635568 | 0.001412057 |
| CLC | 1.853046847 | 0.010293129 | CTSB | − 1.776261192 | 0.012873076 |
| EGR3 | 1.843233413 | 0.003359614 | ANXA3 | − 1.767371637 | 0.010699241 |
| LOC100507481 | 1.77545701 | 0.001358476 | RIOK3 | − 1.762783691 | 0.006681225 |
| ZNF827 | 1.764674234 | 0.01536046 | MAOB | − 1.758125128 | 0.00024905 |
| HSD17B3 | 1.757453949 | 0.0062133 | LOC729870 | − 1.757276671 | 0.035413402 |
| IFT52 | − 1.752051545 | 0.014110306 |