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. 2022 Oct 28;25(11):105455. doi: 10.1016/j.isci.2022.105455

Figure 6.

Figure 6

Vaccine-induced SARS-CoV-2-specific CD8+T cells

(A–C) Frequency of Spike-specific CD25+CD8+T cell (left panel) and fold change (right panel) in CVID (n = 12, black circles), unPAD (n = 9, black triangles), other PADs (CID: n = 1, open triangles and TID: n = 1, open circles), and HC groups (n = 10, black diamonds) after vaccination. Comparison of CD25+CD8+T cell frequency among CVID, unPAD, and HC groups at w8 (B) and w28 versus w8 (C). In (B), Box-whiskers plots showing Min, Max, median and interquartile range are shown and in (A) lines indicate median.

Data in (A) was analyzed using Wilcoxon signed rank test. Data in (B and C) were analyzed using Dunn’s Multiple Comparison Test. ∗p<0.05; ∗∗p<0.01; ∗∗∗p < 0.001. Horizontal dotted line indicates limit of detection.