Figure 2. Frequency of rs4864950 AA, TA, and TT genotypes associated with (A) sorafenib-induced grade 2–3 composite toxicity in TARGET study, (B) sorafenib-induced grade 3 composite toxicity in CALGB 80802, and (C) regorafenib-induced grade 2–3 composite toxicity in the Italian cohort.
The number above each bar represents the number of patients in each genotype.