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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Hepatology. 2022 May 24;77(1):256–267. doi: 10.1002/hep.32545

Table 2.

Final Multivariable Model of the SAFE Score

Variable Estimate Odds Ratio p-value
Age (years) 0.036 (0.009) 1.036 (1.019 – 1.054) <0.0001
BMI* (kg/m2) 0.072 (0.020) 1.075 (1.033 – 1.118) 0.0004
Diabetes 0.754 (0.227) 2.126 (1.363 – 3.317) 0.0009
Ln(AST) (U/L) 1.858 (0.335) 6.412 (3.333 – 12.34) <0.0001
Ln(ALT) (U/L) −0.699 (0.281) 0.497 (0.287 – 0.863) 0.0130
Ln(Globulin)** (g/dL) 2.346 (0.568) 10.44 (3.433 – 31.75) <0.0001
Ln(Platelet Count) (109/L) −1.699 (0.340) 0.183 (0.094 – 0.356) <0.0001
*

BMI > 40 kg/m2 was set to 40 kg/m2

Ln, Natural Logarithm; BMI, Body Mass Index; AST, aspartate aminotransferase; ALT, alanine aminotransferase

**

Globulin = Total Protein - Albumin