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. 2022 Oct 27;13(10):904. doi: 10.1038/s41419-022-05348-w

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© The Author(s) 2022, corrected publication 2022

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Fig. 2 — A–E The body weight (A), fasting blood glucose level (B), fasting serum insulin level (C), fed blood glucose level (D) and fed serum insulin level (E) of Rosa-Reg1cp-wt, Rosa-Reg1cp-mut, Reg1cp-wt_RIP⁺ and Reg1cp-mut_RIP⁺ mice under regular diet. F–I The GTTs (F) and ITTs (H) in Reg1cp-wt_RIP⁺, Reg1cp-mut_RIP⁺ mice and related Rosa-Reg1cp-wt and Rosa-Reg1cp-mut controls under regular diet. Bar graphs showing the calculated values for area under curve (AUC) during the 120-min test course of the GTTs (G) and ITTs (I) (mg dl⁻¹ × 120 min × 10³). J–M The GTTs (J) and ITTs (L) in Reg1cp-wt_RIP⁺, Reg1cp-mut_RIP⁺ mice and related Rosa-Reg1cp-wt and Rosa-Reg1cp-mut controls under HFD. Bar graphs showing the calculated values for area under curve (AUC) during the 120-min test course of the GTTs (K) and ITTs (M) (mg dl⁻¹ × 120 min × 10³). n = 6 in each group from three independent experiments. Data shown as mean ± SD. *P < 0.05; **P < 0.01; NS no significance; One-way ANOVA.