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. 2022 Oct 14;13:888677. doi: 10.3389/fphar.2022.888677

TABLE 1.

Number of hospital admissions by age-group and study period.

All years Period 1 Period 2
2007–2018 2007–2012 2013–2018
N = 692,522 N = 304,378 N = 388,144
Total admissions a N (%) N (%) N (%) Age-group vs 35–49 IRR (95% CI) a
18–35 years 129,687 (18.7) 57,405 (18.9) 72,282 (18.6) 1.14 (1.06, 1.21)<0.001
35–49 years 113,558 (16.4) 52,564 (17.3) 60,994 (15.7) 1.00 (Reference group)-
50–64 ears 143,416 (20.7) 64,731 (21.3) 78,685 (20.3) 1.26 (1.17, 1.36)p < 0.001
65–79 years 97,611 (25.15) 74,166 (24.4) 97,611 (25.15) 1.50 (1.40, 1.61)<0.001
80 + years 78,572 (20.2) 55,512 (18.2) 78,572 (20.2) 1.17 (1.05, 1.29)p = 0.003
Period 2 vs period 1 IRR (95% CI) a
All ages 304,378 (100.0) 388,144 (100.0) 1.27 (1.22, 1.33) p < 0.001
Daily admission rate N/day Mean (SD) N/day Mean (SD) N/day Mean (SD) Period 2 vs period 1 IRR (95% CI) a
18–35 years 29.6 (9.6) 26.2 (8.9) 33.0 (9.1) 1.26 (1.24, 1.28) p < 0.001
35–49 years 25.9 (9.5) 24.0 (9.2) 27.8 (9.4) 1.16 (1.14, 1.19) p < 0.001
50–64 years 32.7 (12.3) 29.5 (10.8) 35.9 (12.9) 1.22 (1.19, 1.24) p < 0.001
65–79 years 39.2 (15.3) 33.8 (12.4) 44.6 (16.1) 1.32 (1.29, 1.35) p < 0.001
80 + years 30.6 (11.0) 25.3 (8.6) 35.9 (10.5) 1.42 (1.39, 1.44) p < 0.001
All ages 31.6 (12.5) 27.8 (10.7) 34.4 (13.1) 1.28 (1.26, 1.29) p < 0.001
Admissions per patient Mean (SD) Mean (SD) Mean (SD) Period 2 vs Period 1 IRR (95% CI) b
18–35 years 1.85 (6.1) 1.8 (4.6) 1.9 (7.1) 1.047 (1.000, 1.098)p = 0.054
35–49 years 2.1 (9.7) 2.1 (10.2) 2.1 (9.3) 1.008 (0.932, 1.091)p = 0.836
50–64 years 2.6 (14.0) 2.6 (16.0) 2.6 (12.1) 0.981 (0.894,1.076)p = 0.679
65–79 years 3.1 (17.5) 3.2 (18.4) 3.0 (16.8) 0.957 (0.870, 1.053)p = 0.369
80 + years 3.3 (18.2) 3.2 (17.3) 3.5 (18.9) 1.095 (0.983, 1.220)p = 0.099
All ages 2.5 (13.3) 2.5 (13.7) 2.5 (13.1) 1.024 (0.984, 1.066)p = 0.243

N, Number; CI, Confidence Interval; IRR, Incidence rate ratio; SD, standard deviation.

a

Obtained using negative binomial regression and robust standard errors with age-group and period as fixed effects and the sum of all adult admissions each day as the dependent variable.

b

Obtained using negative binomial regression and robust standard errors with age-group and period as fixed effects and the sum of an individual patient’s admissions as the dependent variable.