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. 2022 Oct 14;13:932047. doi: 10.3389/fmicb.2022.932047

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Copyright © 2022 Wang, Wu, Wang, Yang, Bian, Jiang, Lv, Yan, Xia, Han and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Post-antibiotic administration of Akkermansia muciniphila reshaped microbial reconstruction during tumorigenesis. PCoA plot based on Bray-Curtis distance showing the evolution of the gut microbial structure during the development of tumorigenesis in the Control, AOM/DSS, AOM/DSS + Abx, and AOM/DSS + Abx + Akk groups. Week 2: after AOM injection, week 5: after the first cycle of DSS treatment, week 8: after the second cycle of DSS treatment, and week 12: after the third cycle of DSS treatment and before sacrifice.