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. 2022 Oct 14;13:930252. doi: 10.3389/fimmu.2022.930252

Figure 2.

Figure 2

HCWs who recovered from an asymptomatic SARS-CoV-2 infection demonstrate partial immune response after one dose of vaccine. (A) SARS-CoV-2 Spike RBD–specific binding IgG levels assessed by ELISA (left panel), SARS-CoV-2 neutralizing antibody titers (middle panel), IFN-γ secreting cells per million in response to SARS-CoV-2 Spike glycoprotein peptides (right panel) assessed by ELISpot for asymptomatic (Asympt.) (n=19) and symptomatic (Sympt.) (n=36) recovered HCWs after one dose of vaccine. Dashed black lines indicate the positive threshold value, and the percentage of HCWs with responses above positive threshold value is indicated for each assay. Horizontal bars indicate the median of each group. Statistical significance was assessed by Mann-Whitney tests. *P <.05; **P <.01; ****P <.0001. (B) Pie charts of calculated immunity score for asymptomatic (left panel) and symptomatic (right panel) recovered HCWs after one dose of vaccine.