TABLE 5.
Cross-reactivitya
| Microsphere | % Cross-reactivity with incubated cytokine
|
|||||
|---|---|---|---|---|---|---|
| IL-4 | IL-6 | IL-10 | IL-12 | IFNγ | TNFα | |
| IL-4 | 100 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 |
| IL-6 | 0.28 | 100 | 0.01 | 0.03 | 0.02 | 0.05 |
| IL-10 | 0.01 | 0.00 | 100 | 0.00 | 0.01 | 0.02 |
| IL-12 | 0.00 | 0.00 | 0.00 | 100 | 0.00 | 0.00 |
| IFN-γ | 0.00 | 0.00 | 0.00 | 0.00 | 100 | 0.00 |
| TNF-α | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 100 |
a
Determined by assays in which each cytokine in turn was incubated, at a concentration of 10 ng/ml, with the microsphere mixture. Results, given in percentages, are calculated as the ratio of the concentration found to the concentration incubated.