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. 2022 Oct 14;9:1013055. doi: 10.3389/fnut.2022.1013055

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Copyright © 2022 Zamani, Zarei, Nikbaf-Shandiz, Hosseini, Shiraseb and Asbaghi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Funnel plots for the effect of berberine consumption on (A) TG (mg/dl); (B) TC (mg/dl); (C) LDL (mg/dl); (D) HDL (mg/dl); (E) FBG (mg/dl); (F) Insulin (mg/dl); (G) HbA1c (%); (H) HOMA-IR; (I) SBP (mmHg); (J) DBP (mmHg); (K) CRP (mg/L); (L) IL-6 (ng/L); (M) weight (kg); (N) BMI (kg/m²); (O) WC (cm); (P) ALT (U/L); and (Q) AST (U/L). TG, triglyceride; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FBG, fasting blood glucose; HOMA-IR, homeostasis model assessment for insulin resistance; hemoglobin A1c, HbA1c; CRP, C-reactive protein; IL-6, interleukin 6; WC, waist circumference; ALT, alanine transaminase; AST, aspartate transaminase; SBP, systolic blood pressure; DBP, diastolic blood pressure; CI, confidence interval, weighted mean difference; WMD.