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. Author manuscript; available in PMC: 2023 Mar 30.
Published in final edited form as: Science. 2022 Sep 30;377(6614):eabo7257. doi: 10.1126/science.abo7257

Fig. 1. Transcriptomically-defined cell taxonomy of anthropoid primate dlPFC.

Fig. 1.

(A) Species (human – red; chimpanzee – blue; macaque – green; marmoset – yellow) and homologous dlPFC areas (blue) analyzed using snRNA-seq. (B) Overview of the snRNA-seq dataset, depicting information from innermost to outermost as: UMAP of all nuclei; dendrogram of hierarchically related subtypes; subtype proportions; marker gene expression; species representation in each subtype (color conforming to panel A); 4 classes; 29 subclasses; 114 refined subtypes. The subtypes detected only in some species are highlighted. See fig. S3A for a more detailed description. IT, intratelencephalic; ET, extratelencephalic; NP, near-projecting; CT, corticothalamic; ChC, chandelier cells; Astro, astrocyte; Micro, microglia; Oligo, oligodendrocytes; OPC: oligodendrocyte precursor cells; Endo, endothelial cells; RB, red blood lineage cells; PC, pericyte; SMC, smooth muscle cells; VLMC, vascular leptomeningeal cell.