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The interaction between COVID-19 and osteosarcopenia could be bidirectional and trigger a vicious circle. Indeed, factors associated with SARS-CoV-2 infection, such as social isolation, sedentariness and malnutrition, are known to promote osteosarcopenia. Conversely, events triggering osteosarcopenia, such as inflammatory reaction and metabolic dysfunction, are also factors associated with COVID-19 disease.
