Figure 1. Meta-analysis of the Prevalence of Dry Eye in the US Population.

A, Prevalence reported in studies without high risk of bias and judged to be representative of the general population. B, Prevalence reported in studies without high risk of bias and judged to be representative of the general population plus Lee et al⁴⁰ (a nationwide Veterans Affairs health system database study with a 95.1% male population). C, Prevalence reported in studies without high risk of bias and judged to be representative of the general population plus Lee et al⁴⁰ (a nationwide Veterans Affairs health system database study with a 95.1% male population) and Chang et al⁴⁴ (a single-institution clinic-based study that used consecutive enrollment from a comprehensive eye clinic in Miami, Florida).