Table 2.
Disease activity according to treatment
| All patients (n = 378) |
Using only NSAID (n = 42) |
Using only TNFi (n = 281) |
Using both TNFi and NSAID (n = 55) |
P-value | ||
|---|---|---|---|---|---|---|
| BASDAI score - n (%) | < 0.01* | |||||
| Inactive disease (< 2) | 103 (27.25) | 2 (4.76) | 97 (34.52) | 4 (7.27) | ||
| Low activity/suboptimal control (≥ 2 and < 4) | 90 (23.81) | 9 (21.43) | 75 (26.69) | 6 (10.91) | ||
| Active disease (≥ 4) | 185 (48.94) | 31 (73.81) | 109 (38.79) | 45 (81.82) | ||
| BASDAI mean (SD) | 4.06 (2.67) | 6.07 (2.50) b | 3.43 (2.50) a | 5.77 (2.09) b | < 0.01** | |
| ASDAS-CRP score - n (%) | < 0.01* | |||||
| Inactive disease (< 1.3) | 36 (26.28) | 1 (5.26) | 33 (34.38) | 2 (9.09) | ||
| Low activity/suboptimal control (≥ 1.3 - <2.1) | 31 (22.63) | 2 (10.53) | 28 (29.17) | 1 (4.55) | ||
| High activity (≥ 2.1 - <3.5) | 49 (35.77) | 11 (57.89) | 25 (26.04) | 13 (59.09) | ||
| Very high activity (≥ 3.5) | 21 (15.33) | 5 (26.32) | 10 (10.42) | 6 (27.27) | ||
| ASDAS-CRP mean (SD) | 2.28 (1.18) | 3.01 (0.90) b | 1.96 (1.07) a | 3.07 (1.24) b | < 0.01** | |
AS ankylosing spondylitis, ASDAS-CRP Ankylosing Spondylitis Disease Activity Score, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, NSAID nonsteroidal anti-inflammatory drug, SD standard deviation, TNFi tumor necrosis factor inhibitors