Table 1.
Characteristics of Included Patients with Enterobacterales Bloodstream Infections
| Variable | APBL≤72 Hours (N=292) No. (%) a |
APBL>72 Hours (N=155) No. (%) a |
P
Value |
|---|---|---|---|
| Age, median y (IQR) | 62 (51–71) | 62 (51–72) | .87 |
| Sex, female | 129 (44) | 63 (41) | .47 |
| Race | |||
| White | 155 (53) | 72 (48) | .27 |
| Black | 124 (43) | 78 (50) | |
| Other | 13 (5) | 5 (3) | |
| Any documented allergy | 177 (61) | 90 (58) | .60 |
| ALT, median (IQR) | 33 (20–75) | 34 (17–60) | .28 |
| AST, median (IQR) | 41 (26–87) | 40 (23–73) | .20 |
| Chronic kidney disease | 68 (23) | 43 (28) | .30 |
| Diabetes | 91 (31) | 55 (36) | .35 |
| Indwelling catheter | 95 (33) | 54 (35) | .62 |
| Skilled nursing facility resident | 12 (4.1) | 8 (5.2) | .61 |
| Intraabdominal source of infection | 118 (40) | 55 (36) | .31 |
| Empirical combination therapy | 98 (34) | 53 (34) | .89 |
| Prior antibiotics in last 3 months | 121 (41) | 56 (36) | .28 |
| Primary definitive therapy with ceftriaxone or fluoroquinolones | 49 (17) | 22 (14) | .48 |
| Charlson comorbidity index, median (IQR) | 5 (3–8) | 6 (3–8) | .33 |
| LOS prior to BSI ≥2 days | 77 (26) | 48 (31) | .30 |
| Pitt bacteremia score | .26 | ||
| 0 | 157 (54) | 71 (46) | |
| 1–2 | 69 (24) | 41 (27) | |
| ≥3 | 66 (23) | 43 (28) | |
Note. APBL, antipseudomonal β-lactam; BSI, bloodstream infection; IQR, interquartile range; LOS, length of stay.
a
Units unless otherwise specified.