Table 3.
Logistic regression predicting subsequent surgical site infections (univariate and multivariate analysis)
| Characteristic | Univariate (Unadjusted) | Multivariate (Adjusted) | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | |
| Age | 0.99 | 0.98–1.00 | .19 | 0.99 | 0.97–1.00 | .09 |
| Sex, male | 1.31 | 0.78–2.22 | .31 | 1.27 | 0.71–2.32 | .40 |
| Duration of surgery, median h (IQR) | 1.01 | 0.90–1.12 | .84 | 1.04 | 0.91–1.17 | .50 |
| Emergency procedure | 2.52 | 1.10–5.06 | .031 | 1.97 | 0.73–4.53 | .14 |
| Charlson comorbidity index | 1.05 | 0.91–1.17 | .50 | 1.05 | 0.91–1.18 | .40 |
| Perioperative antibiotic regimen | <.001 | |||||
| Cefazolin | 1 | 1 (reference) | 1 | 1 (reference) | ||
| Vancomycin | 0.59 | 0.50 | .20 | |||
| Clindamycin | 0.38 | 0.22–1.28 | 0.43 | 0.15–1.24 | .40 | |
| Vancomycin + Cefazolin | 0.13 | 0.02–1.76 | 0.17 | 0.02–1.99 | <.001 | |
| Vancomycin + Cefepime | 0.00 | 0.04–0.32 | 0.00 | 0.005–0.42 | >.90 | |
Note. OR, odds ratio; CI, confidence interval; IQR, interquartile range.