FIGURE 5.

H & E-stained hippocampal sections revealing the cornu amonnis region 1 (CA1): (A,B) C and N groups, respectively showed its pyramidal cell layer formed of small pyramidal neurons with large vesicular nuclei and prominent nucleoli (arrows). (C) AlCl₃ group showed that most of the pyramidal neurons appeared to be deeply stained with pyknotic nuclei (dotted arrows). (D) The group treated with both AlCl₃ and N showed that most of pyramidal neurons appeared normal with large vesicular nuclei and prominent nucleoli (arrows). However, some pyramidal neurons appeared deeply stained with pyknotic nuclei (dotted arrows) (H & E, × 200). (E) Pyramidal cell count of all studied groups. n = 6 in each group. Data were prescribed as mean ± SD. The intergroup variation was conducted by Games-Howell post-hoc test. *p < 0.001 compared with C group. ^#p = 0.004 compared with AlCl_3. ^$p < 0.001 compared with AlCl₃.