Table 1.
Baseline characteristics, N = 122, n (%) unless otherwise specified
| Overall (wgt. N = 122.0) n (%) or mean (SD) |
Statin Users (wgt. N = 9.4a) n (%) or mean (SD) |
Statin Non-users (wgt. N = 112.6) n (%) or mean (SD) |
p-value** | |
|---|---|---|---|---|
| Age, mean (SD) | 55.5 (9.1) | 61.7 (8.9) | 55.0 (9.0) | 0.031 |
| Female | 68.0 (55.7) | 3.8 (40.9) | 64.2 (57.0) | 0.340 |
| BMI, mean (SD) | 26.1 (4.0) | 29.5 (4.2) | 25.8 (3.9) | 0.007 |
| Hypertension | 18.9 (15.5) | 2.6 (27.5) | 16.4 (14.5) | 0.293 |
| Dyslipidemia | 15.9 (13.1) | 6.2 (66.1) | 9.7 (8.7) | < 0.001 |
| Cardio/cerebrovascular disease | 5.0 (4.1) | 1.9 (20.5) | 3.1 (2.8) | 0.009 |
| Diabetes Mellitus | 10.4 (8.5) | 3.6 (38.9) | 6.8 (6.0) | < 0.001 |
| KL grade | < 0.001 | |||
| 0 | 49.7 (40.8) | 0.8 (8.1) | 49.0 (43.5) | |
| 1 | 24.0 (19.7) | 1.1 (11.3) | 23.0 (20.4) | |
| 2 | 27.4 (22.5) | 0.9 (9.2) | 26.6 (23.6) | |
| 3 | 13.8 (11.3) | 4.7 (49.6) | 9.1 (8.1) | |
| 4 | 7.1 (5.8) | 2.0 (21.8) | 5.0 (4.5) | |
| WOMAC pain, mean (SD) | 19.1 (17.3) | 24.7 (21.2) | 18.6 (17.0) | 0.304 |
| WOMAC function, mean (SD) | 16.8 (17.3) | 25.5 (17.5) | 16.1 (17.2) | 0.111 |
| WOMAC stiffness, mean (SD) | 23.3 (23.0) | 45.7 (29.6) | 21.4 (21.3) | 0.002 |
| Max cartilage damage score | 0.209 | |||
| 0/1 | 18.4 (15.1) | 0.0 (0.0) | 18.4 (16.4) | |
| 2 | 34.2 (28.0) | 1.8 (19.4) | 32.4 (28.7) | |
| 3 | 39.5 (32.4) | 2.9 (30.5) | 36.7 (32.6) | |
| 4 | 29.9 (24.5) | 4.7 (50.1) | 25.2 (22.4) | |
| Max osteophytes score | 0.093 | |||
| 0 | 6.8 (5.6) | 0.0 (0.0) | 6.8 (6.1) | |
| 1 | 52.5 (43.0) | 1.8 (19.4) | 50.6 (45.0) | |
| 2 | 49.3 (40.4) | 4.5 (47.8) | 44.8 (39.8) | |
| 3 | 13.4 (11.0) | 3.1 (32.8) | 10.3 (9.2) | |
| Max BML score | 0.758 | |||
| 0 | 53.3 (43.7) | 2.8 (30.4) | 50.5 (44.8) | |
| 1 | 26.6 (21.8) | 1.8 (19.5) | 24.8 (22.0) | |
| 2 | 29.5 (24.2) | 3.2 (33.9) | 26.3 (23.4) | |
| 3 | 12.5 (10.3) | 1.5 (16.2) | 11.0 (9.8) | |
| MRI effusion | 0.905 | |||
| 0 | 31.3 (25.6) | 1.7 (17.7) | 29.6 (26.3) | |
| 1 | 54.6 (44.8) | 5.1 (54.7) | 49.5 (43.9) | |
| 2 | 30.9 (25.3) | 2.1 (22.0) | 28.8 (25.6) | |
| 3 | 5.2 (4.3) | 0.5 (5.6) | 4.7 (4.2) |
aOur analysis is population weighted using decade-gender stratum sampling weights, and the reported numbers are weighted numbers
** Chi-square test for categorical/binary variables, or t-test for continuous variables