Metabolomic profiling of V. alginolyticus in the presence of glycine, serum or serum plus glycine (serum + gly). A. Heat map of metabolites. Yellow and blue color indicate increase and decrease of metabolites relative to the median metabolite level, respectively (see color scale). B. Venn diagram comparing metabolites enriched in each experimental group: glycine (gray), serum (red) and serum + gly (blue). C. D. Enriched pathways and abundance of differential metabolites. E. PCA analysis of control, glycine, serum, and serum + gly group. F. Normalized abundance of l-cysteine. Results are displayed as mean ± SEM, and significant differences are identified. **p < 0.01. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)