Table 1:
Review of cases of Lodderomyces elongisporus infection
| Case report | Demographics | Location | Comorbid conditions | Site of isolate | Method of identification | Presence of central catheter | Management | Clinical outcome |
|---|---|---|---|---|---|---|---|---|
| Present case | Male, aged 62 y | Canada |
Rectal adenocarcinoma Lymphopenia |
Arachnoid biopsy | Fungal ITS sequencing | No |
Lumbar drain insertion Liposomal amphotericin + voriconazole followed by indefinite fluconazole |
Survived |
| Al-Obaid et al (3) | Female, aged 71 y | Kuwait |
Hypertension Coronary artery disease Peripheral vascular disease Stroke |
Blood | Fungal ITS sequencing | No | Caspofungin | Died |
| Lee et al (6) | Female, aged 56 y | Korea |
Lung cancer MRSA Bacteremia |
Blood |
MALDI-TOF Fungal ITS sequencing |
Yes | None | Died |
| Fernandez-Ruiz et al (4) | Male, aged 79 y | Spain |
Chronic obstructive pulmonary disease Diabetes End-stage renal disease |
Blood | Fungal ITS sequencing | Yes | Caspofungin | Died |
| Hatanaka et al (5) | Male, aged 39 y | Japan | Thoracoabdominal aortic replacement complicated by aorto-esophageal fistula | Blood + catheter tip | Fungal ITS sequencing | Yes | Micafungin | Survived |
| Taj-Aldeen et al (7) | Male, aged 22 y | Qatar | Trauma | Blood |
MALDI-TOF Fungal ITS sequencing |
Unknown |
Caspofungin Fluconazole |
Died |
| Ahmad et al (9) | Male, aged 63 y | Kuwait |
Cardiovascular attack Schizophrenic-like condition |
Central catheter tip | Fungal ITS sequencing | Yes | Fluconazole | Survived |
| Daveson & Woods (10) | Male, aged 30 y | Australia |
Endocarditis Embolic stroke Osteomyelitis Injection drug use |
Aortic valve + blood | Fungal ITS sequencing | Yes |
Aortic valve replacement Caspofungin x 2 wk pre-operatively Liposomal amphotericin + 5-flucytosine x 6 wk, then voriconazole x 7.5 mo |
Survived |
| Thompson et al (11) | Male, aged 46 y | United States |
Mechanical aortic valve Hepatitis C Injection drug use |
Blood |
MALDI-TOF Fungal ITS sequencing |
No |
Cefepime + vancomycin + micafungin Switched to liposomal amphotericin + flucytosine x 6 wk |
Survived |
| Koh et al (8) | Female, aged 54 y | Australia |
Total colectomy + ileostomy Short gut syndrome Total parenteral nutrition |
Blood | MALDI-TOF | Yes |
Anidulafungin x 20 d (14 d after line removal) Central catheter removal |
Survived |
ITS = Internal transcribed spacer; MRSA = Methicillin-resistant Streptococcus aureus; MALDI-TOF = Matrix-assisted laser desorption ionization-time of flight