. Author manuscript; available in PMC: 2022 Oct 28.

Published in final edited form as: Brain Behav Immun. 2022 Feb 5;101:397–409. doi: 10.1016/j.bbi.2022.02.004

Table 7.

Linear mixed effect models with CTQ subscale scores (natural-log transformed) as predictor and proinflammatory score as outcome variable.

	Model M5: CTQ subscale score: Emotional Abuse (EA)			Model M5: CTQ subscale score: Physical Abuse (PA)			Model M5: CTQ subscale score: Sexual Abuse (SA)			Model M5: CTQ subscale score: Emotional Neglect (EN)			Model M5: CTQ subscale score: Physical Neglect (PN)
	Estimates	SE	p	Estimates	SE	p	Estimates	SE	p	Estimates	SE	p	Estimates	SE	p

Regression coefficients

Intercept	−0.27	0.09	0.004	−0.27	0.09	0.004	−0.28	0.09	0.003	−0.26	0.09	0.005	−0.26	0.09	0.005
Maternal race/ethnicity (Ref. Non-Hispanic White)
Hispanic	0.12	0.11	0.274	0.13	0.11	0.232	0.16	0.11	0.142	0.14	0.11	0.217	0.14	0.11	0.201
Non-Hispanic Other	−0.05	0.14	0.718	−0.03	0.14	0.808	−0.00	0.14	0.980	−0.04	0.14	0.757	−0.03	0.14	0.837
Pre-pregnancy BMI	0.05	0.01	<0.001	0.05	0.01	<0.001	0.05	0.01	<0.001	0.05	0.01	<0.001	0.05	0.01	<0.001
Lifetime psychiatric in-patient treatment (Ref. No)
Yes	0.09	0.22	0.681	0.16	0.22	0.463	0.22	0.22	0.317	0.15	0.22	0.512	0.17	0.22	0.461
Presence of any obstetric risk condition (Ref. No)
Yes	−0.16	0.13	0.198	−0.17	0.13	0.184	−0.16	0.13	0.201	−0.14	0.13	0.261	−0.17	0.13	0.186
Pharmacological treatment of anxiety/depression during pregnancy (Ref. No)
Yes	−0.43	0.36	0.230	−0.49	0.36	0.170	−0.42	0.36	0.243	−0.45	0.36	0.207	−0.50	0.36	0.162
SES	0.04	0.06	0.514	0.03	0.06	0.594	0.03	0.06	0.576	0.05	0.06	0.392	0.03	0.06	0.661
Gestational age	0.02	0.00	<0.001	0.02	0.00	<0.001	0.02	0.00	<0.001	0.02	0.00	<0.001	0.02	0.00	<0.001
CES-D score	−0.00	0.00	0.945	0.00	0.00	0.510	0.00	0.00	0.415	0.00	0.00	0.702	0.00	0.00	0.345
CTQ subscale score (ln)	0.09	0.12	0.473	−0.02	0.02	0.250	−0.24	0.14	0.090	0.12	0.12	0.305	−0.16	0.16	0.320
*CTQ subscale score (ln) CES-D score**	0.03	0.01	0.002	0.00	0.00	0.015	0.02	0.01	0.066	0.01	0.01	0.172	0.02	0.01	0.105
Variance components
Within-person variance σ²	0.30			0.31			0.31			0.31			0.31
Between-person variance τ₀₀	0.24 _participant			0.24 _participant			0.24 _participant			0.25 _participant			0.24 _participant
Model summary
Observations	498			498			498			498			498
N (participants)	180 _participant			180 _participant			180 _participant			180 _participant			180 _participant
Pseudo R²	0.190			0.180			0.177			0.173			0.173

Note. SE = standard error; BMI = Body-Mass-Index; SES = socio-economic status; CES-D = Center for Epidemiologic Studies – Depression Scale; CTQ = Childhood Trauma Questionnaire. Outcome: repeatedly-measured aggregated score of serum concentrations of TNF-α and IL-6; Covariates: maternal race/ethnicity, SES, pre-pregnancy BMI, lifetime psychiatric in-patient treatment, presence of any obstetric risk conditions, pharmacological treatment of anxiety/depression during pregnancy; Predictors: Model 5: gestational age, CTQ subscale score (ln), repeatedly-measured CES-D score, CTQ subscale score (ln)*repeatedly-measured CES-D score.