Table 1.

The comparison of different methods for miRNA detection.

Detection platform	Method	Limit of detection (pM)	Linear range (nM)	Refs.
Thiolated DNA probes	Fluorescence	680.0	0–30	[30]
DNA walker	Fluorescence	8.9	0.02–2.5	[31]
Polyadenine-mediated fluorescent spherical nucleic acids	Fluorescence	310.0	0–30	[33]
Lateral flow test	Visual	68.0	0.1–10	[37]
DNA strand displacement	Fluorescence	1.0	0.2–25	[38]
Layered graphene	Electrochemistry	14.6	0.01–100	[39]
Microfluidic electrokinetic enrichment	Fluorescence	1.3	0.01–50	This work