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. 2021 Feb 16;88(6):907–916. doi: 10.1016/j.bjorl.2020.12.017

Table 2.

Characteristics of the included tests.

Study Compadretti et al., 2006 Cappellette Jr. et al., 2017 Izuka et al., 2015 Matsumoto et al., 2016
Design Non-randomized controlled clinical trial Non-randomized controlled clinical trial Non-randomized uncontrolled clinical trial Non-randomized uncontrolled clinical trial
Patients 27 children: 13 boys, 14 girls 23 children: 11 boys, 12 girls 25 children 29 children
Age Mean of 5–13 years (SD = 9.5 years ± 2.1) Mean of 9.6 years (SD = 2.3 years) Mean of 10.5 years (6–13 years, SD = 2.2) 7–10 years
Previous features Upper arch constriction Upper arch constriction Mouth breathing Mouth breathing
Absence of natural causes for nasal respiratory failure Mouth breathing Maxillary atresia Mixed dentures
Mixed dentures Posterior crossbite Unilateral or bilateral posterior crossbite
Enlarged adenoids Nasal obstruction
Obstructive septum
Further tests RMM Quality of life questionnaire Quality of life questionnaire Acoustic Rhinometry
AR EOL: Rhinoscopy; Oroscopy; Nasal fibroendoscopy EOL: Rhinoscopy; Oroscopy; Nasal fibroendoscopy Computerized Rhinomanometry
Audiometry
Tympanometry Nasal fibroscopy
PA X-rays: Internasal distance; Interzygomatic distance; Intermaxillary distance Orthodontic examination: atresia of the upper arch; 3 min test with closed lips; Computed tomography (before RME and 3 months after RME) Computed tomography PA X-rays: NC-NC (corresponding to the internasal width); JL-JL (corresponding to maxillary width)
Group control 24 children: 16 boys, 8 girls 15 children: 9 boys, 6 girls
Age, control group Mean of 8–12 years (10.2 years ± 1.5 SD) 10.5 years (SD = 1.9 years)
Previous characteristics, control group Without obstruction (confirmed by nasopharyngoscopy) Not reported
Tests, control group RAM and AR (first visit and after 11 months on average) Computed Tomography (before RME and 3 months after RME)
Intervention RME with Hyrax RME with Hyrax RME with Bierderman RME with Haas
Country Italy Brazil Brazil Brazil
Follow-up 12 months ± 0.8 SD (mean of 10.3–13.6 months) 3 months 3 months 30 months
Dolphin Imaging v.11.7 software CT + Reconstruction Volumetric measurements and comparisons between the images of both groups were taken to Dolphin and evaluated in “airway volume” in 3 views: sagittal, coronal, and axial. Used to assess the patients' upper airway, using the following measures: ANF: width of the anterior portion of the nasal floor; PNF: width of the posterior portion of the nasal floor; VNN: volume of the nasopharynx and nasal cavity
Conclusion The improvement in nasal breathing after RME is due to the significant increase in nasal width. RME showed a significant increase in the transverse dimension of the maxilla and a significant increase in nasal and oropharyngeal volumes. Significant increase in transverse maxillary distances and significant increase in nasal and oropharyngeal volumes. RME significantly increased the maxillary and nasal transverse distances.