Design |
Non-randomized controlled clinical trial |
Non-randomized controlled clinical trial |
Non-randomized uncontrolled clinical trial |
Non-randomized uncontrolled clinical trial |
Patients |
27 children: 13 boys, 14 girls |
23 children: 11 boys, 12 girls |
25 children |
29 children |
Age |
Mean of 5–13 years (SD = 9.5 years ± 2.1) |
Mean of 9.6 years (SD = 2.3 years) |
Mean of 10.5 years (6–13 years, SD = 2.2) |
7–10 years |
Previous features |
Upper arch constriction |
Upper arch constriction |
Mouth breathing |
Mouth breathing |
Absence of natural causes for nasal respiratory failure |
Mouth breathing |
Maxillary atresia |
Mixed dentures |
Mixed dentures |
Posterior crossbite |
Unilateral or bilateral posterior crossbite |
Enlarged adenoids |
Nasal obstruction |
Obstructive septum |
Further tests |
RMM |
Quality of life questionnaire |
Quality of life questionnaire |
Acoustic Rhinometry |
AR |
EOL: Rhinoscopy; Oroscopy; Nasal fibroendoscopy |
EOL: Rhinoscopy; Oroscopy; Nasal fibroendoscopy |
Computerized Rhinomanometry |
Audiometry |
Tympanometry |
Nasal fibroscopy |
PA X-rays: Internasal distance; Interzygomatic distance; Intermaxillary distance |
Orthodontic examination: atresia of the upper arch; 3 min test with closed lips; Computed tomography (before RME and 3 months after RME) |
Computed tomography |
PA X-rays: NC-NC (corresponding to the internasal width); JL-JL (corresponding to maxillary width) |
Group control |
24 children: 16 boys, 8 girls |
15 children: 9 boys, 6 girls |
– |
– |
Age, control group |
Mean of 8–12 years (10.2 years ± 1.5 SD) |
10.5 years (SD = 1.9 years) |
– |
– |
Previous characteristics, control group |
Without obstruction (confirmed by nasopharyngoscopy) |
Not reported |
– |
– |
Tests, control group |
RAM and AR (first visit and after 11 months on average) |
Computed Tomography (before RME and 3 months after RME) |
– |
– |
Intervention |
RME with Hyrax |
RME with Hyrax |
RME with Bierderman |
RME with Haas |
Country |
Italy |
Brazil |
Brazil |
Brazil |
Follow-up |
12 months ± 0.8 SD (mean of 10.3–13.6 months) |
3 months |
3 months |
30 months |
Dolphin Imaging v.11.7 software CT + Reconstruction |
– |
Volumetric measurements and comparisons between the images of both groups were taken to Dolphin and evaluated in “airway volume” in 3 views: sagittal, coronal, and axial. |
Used to assess the patients' upper airway, using the following measures: ANF: width of the anterior portion of the nasal floor; PNF: width of the posterior portion of the nasal floor; VNN: volume of the nasopharynx and nasal cavity |
– |
Conclusion |
The improvement in nasal breathing after RME is due to the significant increase in nasal width. |
RME showed a significant increase in the transverse dimension of the maxilla and a significant increase in nasal and oropharyngeal volumes. |
Significant increase in transverse maxillary distances and significant increase in nasal and oropharyngeal volumes. |
RME significantly increased the maxillary and nasal transverse distances. |