Figure 2.

Characteristics of SPION synthesized by batch and under flow. TEM micrographs showed spherical particles synthesized by batch (A, D), under continuous flow (B, E), and segmented flow (C, F) with an iron salt concentration ratio of 4.3/8.65 mM, 6.5 M NH₄OH, and 20 mg/mL CMD (A–C) or D70 (D–F) coating. Histograms below TEM micrographs showed size distributions of corresponding samples. TEM (G) and DLS (H) measurements showed a larger iron oxide core and hydrodynamic diameter (d_H) for particles synthesed by batch as compared with those under flow (I).