(A–C) Statistical overrepresentation test was performed with reactome pathways as annotation set. Top overrepresented pathways in Mtb-infected mice lungs at 50 dpi with respective fold enrichment in (A) CD4+ T cell clusters, (B) CD8+ T cell clusters, and (C) B cell clusters. False discovery rate (FDR) <0.05.
(D) Average expression of several IFN-related genes that were differentially expressed in respective lymphoid cell clusters. The dot size represents the percentage of cells in each cluster expressing a particular gene.
See also Figure S3 and Tables S1 and S2.