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Schematic drawing of the medial brain surface with Brodmann areas. Pink: prefrontal lobe, light red: the pyramidal system (A); red: the anterior cingulate area (Br. 24, 25, 32) (B). There is a dissociation during DOA episodes between the blue fronto-dorsal cortex (in partial sleep) and the red anterior cingulate cortex (in partial wakefulness). SHE seizure onset zones of successfully operated SHE patients frequently overlap with DOA episodes' activated red anterior cingulate area.
