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. 2022 Oct 14;13:1011669. doi: 10.3389/fendo.2022.1011669

Figure 1.

Figure 1

Canagliflozin inhibits oxidative stress and fibrosis in diabetic myocardial tissue (A) Pathological staining results of myocardial tissues (Scale bar: 100 µm). (B) CVF of Masson staining. (C) CVF of Sirus red staining. Contents of (D) PCO and (E) MDA, activities of (F) SOD and (G) CAT in myocardial tissues. CVF, collagen volume fraction; PCO, protein carbonyl; MDA, malondialdehyde; SOD, superoxide dismutase; CAT, catalase. (*: P < 0.05; **: P < 0.01; ***: P < 0.001; compared with CON group; #: P < 0.05; ##: P < 0.01; ###: P < 0.001; compared with DCM group; n.s.: no significance.).