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Pathogenesis of cardiovascular toxicity during CAR-T therapy. Abbreviations: CAR, chimeric antigen receptor; CRS, cytokine release syndrome; IL, interleukin; TNF-α, tumor necrosis factor alpha; MAPK, mitogen-activated protein kinase; TLS, tumor lysis syndrome; DIC, disseminated intravascular coagulation; Ang-2, angiopoietin-2; VWF, von willebrand factor. This figure created with BioRender.com.
