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. Author manuscript; available in PMC: 2022 Oct 28.
Published in final edited form as: Chem Rev. 2021 Aug 17;122(11):10126–10169. doi: 10.1021/acs.chemrev.1c00513

Figure 10.

Figure 10.

Energy profiles for C4 versus C6 oxidative addition of 4,6-dichloro-2-pyrone. Relative free energies and reaction energies (in parentheses) listed in kcal/mol (ref 95).