Table 1:

Comparison of Recommendations for Screening of Patients At Risk for Acquiring HBV (Differences between the AASLD and WHO guidelines are in italics)

WHO

AASLD

• Household and sexual contacts of persons with HBV  • Persons infected with HIV  • Persons who inject drugs  • Men who have sex with men  • Persons who are incarcerated  • Blood and organ donors  • Pregnant women  • General population screening in countries with high HBV endemicity

• Persons born in regions of high or intermediate HBV endemicity (HBsAg prevalence of ≥2%)  • US born persons not vaccinated as an infant whose parents were born in regions with HBV endemicity ≥8%)  • Men who have sex with men  • Intravenous drug users  • Individuals needing immunosuppressive therapy, including chemotherapy, immunosuppression related to transplantation, and immunosuppression for various disorders  • Persons with elevated ALT or AST of unknown etiology  • Organ, plasma, blood, tissue or semen donors  • End stage renal disease patients needing dialysis  • All pregnant women and infants born to HBsAg mothers  • Persons infected with Hepatitis C and HIV  • Household and sexual contacts of HBsAg positive persons  • Persons requesting evaluation/treatment of sexually transmitted disease or have multiple sexual partners  • Health care, public safety workers and staff of facilities for developmentally disabled persons  • Persons travelling to countries with intermediate or high HBV prevalence  • Inmates of correctional facilities  • Unvaccinated persons with diabetes with age of 19–59 years.