Table 2.

Acquisition parameters for the imaging protocol. Voxel size in mm. TR/TE/TI all in milliseconds. Acquisition time in minutes and seconds. Flip angle in degrees. CVR =Cerebrovascular reactivity; MPRAGE =Magnetisation-prepared rapid acquisition with gradient echo; FLAIR =Fluid-attenuated inversion recovery; PD =Proton density; SPACE =Sampling perfection with application-optimised contrast using different flip-angle evolution; SWI =Susceptibility weighted imaging; dMRI =Diffusion imaging; pcASL =Pseudo-continuous arterial spin labelling; TOF =Time-of-flight; PC =Phase-contrast; SACSF =Subarachnoid cerebrospinal fluid; IR =Inversion recovery; sGRE =Spoiled gradient recalled echo; TI =Inversion time; FA =Flip angle; DCE =Dynamic contrast-enhanced; TR =Repetition time; TE =Echo time; R=parallel imaging acceleration factor; MB=multiband acceleration factor; NA = number of averages.

	CVR	T1w	FLAIR	PD	T2w	SWI	dMRI	MRA	Flow			Quantitative T1			DCE-MRI
Sequence	2D GE-EPI	MPRAGE (3D IR-sGRE)	SPACE (3D RARE)	3D sGRE	SPACE(3D RARE)	3D sGRE	2D GE-EPI	TOF	2D PC (carotids)	2D PC (SACSF)	2D PC(veins)	3D IR-sGRE	3D IR-sGRE	3D sGRE	T1w 3D sGRE
Voxel Size	2.5 × 2.5 × 2.5	1 × 1 × 1	1 × 1 × 1	1 × 1 × 1	0.9 × 0.9 × 0.9	0.6 × 0.6 × 3	2.0 × 2.0 × 2	0.5 × 0.7 × 1.6	1.0 × 1.0 × 5	0.8 × 0.8 × 5	0.7 × 0.7 × 5	1.2 × 1.2 × 1.2	1.2 × 1.2 × 1.2	1.2 × 1.2 × 1.2	2 × 2 × 2
TR	3000	2500	5000	6.04	3200	28	4300	20.0	19.60	25.18	21.70	1040	1940	5.4	3.44
TE	30.0	4.37	388	2.44	408	20	74.0	3.51	5.82	8.45	6.59	1.82	1.82	1.82	1.68
TI	–	1100	1800	–	–	–	–	–	–	–	–	600	1500	–	–
Flip Angle	90	7	–	2.0	–	9	–	20	12	12	12	5	5	2, 5, 12	15
Acquisition Time	12:30	3:45	5:57	1:57	3:42	4:02	11:16	2:45	1.39 approx.	1:55 approx.	2:11 approx.	1:55	3:35	1:36 × 3	21:08
Other	R = 2	R = 3	R = 3	R = 3	R = 2 × 2	R = 2	R = 2, MB=2, 15 x b = 0 s/mm2, 3 x b = 200 s/mm2, 6 xb=500 s/mm2, 64 x b = 1000s/mm2, 64 x b = 2000s/mm2 (3 x b0 acquired with reversed phase encoding		R = 2 venc=70 cm/s NA=2	R = 2 venc=6 cm/s	R = 2 venc=50 cm/s	R = 2	R = 2	R = 2	vol