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Overview figure of the BOLD acquisitions. Part A (visual stimulus) and B (hypercapnic stimulus) show examples of the (1) image acquisition, (2) voxelwise reactivity maps, and (3) BOLD signal curves over time for small vessel reactivity. For A, amplitude and full-width-at-half-maximum are extracted from the hemodynamic response function. For B, the average% of BOLD signal change to the hypercapnic stimulus is calculated, using the recorded etCO2 trace as the input model for analysis.
