Table 5.
7T brain MRI protocol in fixed order. CSO= Semioval centre; BG= Basal Ganglia; M1= first segment of the middle cerebral artery; BOLD= Blood oxygenation level-dependent; fMRI= functional magnetic resonance imaging; FOV= Field of view; TE= Echo Time; TI= Inversion Time; TR= Repetition Time. *Total scan time for a heart rate of 80 bpm.
| MR sequence | Acquired resolution mm3 | Time min:s | Parameters |
|---|---|---|---|
| T1-weighted | 1.0 × 1.0 × 1.0 | 01:59 | FOV 250 × 250 × 190 mm3; TR 4.2 ms; TI 1297 ms; shot interval 3000 ms; flip angle 5° |
| 2D-Qflow CSO | 0.3 × 0.3 × 2.0 | 03:24* | FOV 230 × 230 mm2; reconstructed resolution 0.18 × 0.18 mm [2]; TR 29 ms; TE 16 ms; Venc 4 cm/s |
| T1-weighteda | 1.0 × 1.0 × 1.0 | 00:47 | FOV 250 × 250 × 190; TR 4.1 ms; TI 1253 ms; shot interval 3000; flip angle 5° |
| 2D-Qflow BG | 0.3 × 0.3 × 2.0 | 03:47* | FOV 170 × 170 mm2; reconstructed resolution 0.18 × 0.18 mm2;TR 28 ms; TE 15 ms; Venc 20 cm/s |
| 2D-Qflow M1 | 0.5 × 0.5 × 3.0 | 01:47* | FOV 250 × 200 mm2; TR 12 ms; TE 4.3 ms; Venc 100 cm/s |
| T2* whole brain | 0.6 × 0.6 × 0.6 | 03:02 | FOV 239 × 191 × 100 mm3; TR 77 ms; TE 27 ms; flip angle 20° |
| T2* visual cortex | 0.6 × 0.6 × 1.0 | 02:21 | FOV 160 × 169 × 29 mm3; TR 1250 ms; TE 16 ms; flip angle 40° |
| BOLD fMRI visual cortexb |
1.3 × 1.3 × 1.3 | 10:05 | FOV 140 × 140 × 11 mm3; TR 880 ms; TE 25 ms |
| T1-weighteda | 1.0 × 1.0 × 1.0 | 00:47 | FOV 250 × 250 × 190 mm3; TR 4.1 ms; TI 1253 ms; shot interval 3000; flip angle 5° |
| BOLD fMRI whole-brainc |
2.0 × 2.0 × 2.0 | 10:00 | FOV 224 × 256 × 101 mm3; TR 3000 ms; TE 25 ms |
a
A fast version of the T1-weighted sequence was added multiple times to assess potential subject motion during the scan, particularly after repositioning for attaching the mask for the hypercapnic challenge.
b
The participant is presented with a visual stimulus.
c
The participant undergoes a hypercapnic challenge.