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Accumulation of diffuse parenchymal Aβ deposits in rTg-D rats. Brain sections from 12 to 24 M old rTg-D rats were immunolabeled for Aβ (green) and for collagen type IV to identify cerebral vessels (red). Representative images show diffuse parenchymal Aβ deposits in the cortex of 12 M (A), 18 M (B) and 24 M (C) rTg-D rats. Scale bars = 50 µm. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
