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Gene expression of p19ARF (Panel A), p21 (Panel B), and p53 (Panel C) in BMSCs that were treated or not treated with REAC TO-RGN for 24, 48, or 72h. The expression of each gene increased for each time point in the untreated control cells, while it was significantly downregulated in the REAC TO-RGN-treated cells (mean ± SD; n=6) (* p≤0.05; ** p≤0.01).
