TABLE 5.

List of metabolites in AT against AC.

Mode	Metabolite	ID	MW	RT	FC
+	Acetylcholine	HMDB0000895	145.11005	0.655	−1.21
+	Adenine	HMDB0000034	135.05422	0.842	+2.05
+	Adenosine monophosphate/3′-Adenosine monophosphate	HMDB0000045/HMDB0003540	347.06241	0.857	+1.54
+	Aspartic acid	HMDB0000191/HMDB0006483	133.0374	0.503	+1.26
+	Ketamine	HMDB0015352	237.09164	4.973	+4.68
+	N6-Me-Adenosine	mzc10245	281.11165	1.018	+1.61
+	N-Acetylaspartylglutamic acid	HMDB0001067	304.08996	1.421	+1.33
+	Nicotinamide adenine dinucleotide	HMDB0000902	663.10799	1.151	+7.79
+	Prolylglycine	HMDB0011178	172.08458	0.631	+1.95
+	Prolylleucine	mzc559	228.14719	1.275	+1.54
+	Pyroglutamic acid	HMDB0000267	129.04241	1.087	+1.40
+	Spermine	HMDB0001256	202.21555	0.369	+3.56
+	Uric acid	HMDB0000289	168.02815	0.955	−1.54
−	Citric acid	HMDB0000094	192.02623	0.911	−17.30
−	Glycerol 3-phosphate	HMDB0000126	172.01282	0.522	+3.74
−	Mannose 6-phosphate/Fructose 1-phosphate/Beta-D-Fructose 6-phosphate/Glucose 1-phosphate/	HMDB0001078/HMDB0001076/HMDB0003971/HMDB0001586/HMDB0001401	260.02945	0.517	−2.84

AC, as denominator.

FC: positive mode (negative mode).

Potential metabolite identified by cross referencing with mzCloud data (^).

Symbol: (+) increase; (-) decrease.

Acronym: FC (fold change); m/w (molecular weight); RT (retention time).