Table 3.

Multivariate logistic regression analysis.

Variable	Crude OR (95% CI)	Adjusted OR (95% CI)
Age at enrollment	1.03 (0.41–2.63)	0.99 (0.94–1.05)
Male sex	2.59 (1.19–5.64)	2.19 (0.77–6.27)
dcSSc subset	3.19 (1.41–7.61)	2.31 (0.67–7.97)
Duration of disease every 1 year	0.99 (0.89–1.11)	1.02 (0.91–1.15)
BMI at onset	0.59 (0.48–0.74)	0.60 (0.48–0.75)*
Anti-topoisomerase I antibody	4.83 (1.11–43.65)	3.16 (0.39–25.92)
High CRP	2.89 (1.30–6.33)	3.18 (1.06–9.54)*
Vitamin D insufficiency	0.34 (0.14–0.78)	0.47 (0.14–1.59)
Anemia at onset	3.99 (1.78–9.32)	2.39 (0.87–6.54)
Prednisolone at enrollment	1.75 (0.82–3.80)	1.04 (0.91–1.18)

95%CI 95% confidence interval, dcSSc diffuse cutaneous systemic sclerosis, BMI body mass index, ESR erythrocyte sedimentation rate, CRP C-reactive protein.

*p < 0.001.