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. 2022 Oct 28;13:6440. doi: 10.1038/s41467-022-33421-7

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© The Author(s) 2022

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Fig. 6 — a Superposition of hSGLT1_outward-oepn (colored) and hSGLT1_inward-open (gray, PDB ID: 7SLA). Helices are shown as cylinders. b The structural alignment of the constant module. c Top view of the moving module. d Bottom view of the moving module. The movement of helices are shown as red arrows. e The conformational changes of the hSGLT1 extracellular gate. f The conformational changes of the hSGLT1 intracellular gate. Residues which moves are shown as sticks, the movement of residues are shown as red arrows.