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. 2022 Oct 28;8:431. doi: 10.1038/s41420-022-01213-z

Fig. 7. Inhibition of FASN reversed the tumor-promoting effects of NUPR1 in HCC cells.

Fig. 7

A, B Effects of LV-NUPR1, FASN inhibitor C75 (50 μM) or co-transfected with LV-NUPR1 and C75 on the proliferation of MHCC-97H and SK-Hep1 cells were evaluated by CCK8 assays (a) and EdU assays, scale bars represent 20 µm (b). C HCC cells transfected with LV-NUPR1, C75 or co-transfected with LV-NUPR1 and C75 were stained with Bodipy 493/503 and images were acquired by confocal microscope. D Transwell migration assays were used to detecte the migrative ability of MHCC-97H and SK-Hep1 cells with LV-NUPR1, C75 or co-transfected with LV-NUPR1 and C75, scale bars represent 25 µm.