Fig. 1. Transcriptional differences between laboratory and clinical isolates of K. pneumoniae.

A Differential expression analysis with Log₂ fold change cutoff = 2.5, p-value cutoff = 0.05. Genes with highest degree of difference are labeled. Each point is an individual gene and the color of the point corresponds to whether or not the Log₂ fold change is not significant (black, NS), has a Log₂ fold change > 2.5 (green, Log₂ FC), has a p-value < 0.05 (blue, p-value), or a Log2 fold change > 2.5 and a p-value < 0.05 (red, p-value and log₂ FC). B–E Median and interquartile ranges for select genes based on previous analysis. Significant differences determined by Wilcoxon rank-sum test with Benjamini–Hochberg correction (***p-value ≤ 0.001, **p-value ≤ 0.01).