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. 2022 Oct 28;12:18209. doi: 10.1038/s41598-022-20277-6

Table 3.

Cardiometabolic markers of participants before and after intervention.

Magnesium-supplemented group Placebo group Difference
Before After Mean difference ± SE P value* Before After Mean difference ± SE P value* P value**
SBP (mmHg) 120.0 ± 20.1 115.7 ± 12.8  − 4.2 ± 4.03 0.30 120.5 ± 13.3 113 ± 24.5  − 7.5 ± 3.7 0.05 0.55
DBP (mmHg) 76.8 ± 13.1 73.9 ± 9.2  − 2. ± 3.2 0.38 79.2 ± 15.7 74.1 ± 13.0  − 5.1 ± 3.2 0.12 0.98
Total-C (mg/dL) 193.1 ± 37.5 188.2 ± 38.7  − 4.9 ± 8.7 0.58 183.6 ± 40.8 176.9 ± 35.5  − 6.7 ± 6.6 0.32 0.36
TG (mg/dL) 156.4 ± 77.9 123.1 ± 48.4  − 33.3 ± 14.0 0.02 158.0 ± 65.3 135.7 ± 51.7  − 22.3 ± 8.9 0.01 0.28
HDL-C (mg/dL) 46.0 ± 11.8 49.7 ± 10.9 3.7 ± 1.1 0.002 42.9 ± 7.8 43.6 ± 7.2 0.7 ± 0.7 0.29 0.003
LDL-C (mg/dL) 99.9 ± 27.3 95.0 ± 24.1  − 4.9 ± 5.3 0.37 97.7 ± 27.4 88.2 ± 22.2  − 9.5 ± 4.2 0.03 0.25
HbA1c (%) 5.8 ± 0.7 6.6 ± 0.8 0.8 ± 0.1  < 0.001 5.8 ± 0.6 6.5 ± 0.8 0.7 ± 0.1  < 0.001 0.55
FPG (mg/dL) 115.1 ± 14.2 116.5 ± 13.7  − 1.5 ± 2.0 0.48 112.5 ± 12.2 111.8 ± 14.3  − 0.7 ± 1.8 0.72 0.29
FPI (μU/mL) 8.2 ± 5.9 16.9 ± 7.8 8.7 ± 1.4  < 0.001 14.8 ± 9.6 17.9 ± 8.4 3.2 ± 1.3 0.02 0.18
Uric acid (mg/dL) 5.2 ± 1.4 4.9 ± 1.1  − 0.2 ± 0.2 0.28 4.8 ± 1.1 5.1 ± 1.0 0.26 ± 0.1 0.04 0.09
CRP (mg/L) 1.3 ± 2.7 3.1 ± 4.0 1.8 ± 0.5 0.001 1.3 ± 2.6 2.2 ± 2.1 0.8 ± 0.4 0.03 0.10
HOMA-IR index 3.1 ± 4.4 4.9 ± 2.5 1.8 ± 0.9 0.06 4.0 ± 2.8 4.9 ± 2.6 0.9 ± 0.4 0.02 0.80

SBP systolic blood pressure, DBP diastolic blood pressure, C cholesterol, TG triglyceride, FPG fasting plasma glucose, fasting plasma insulin, CRP C-reactive protein.

*Resulted from paired t-test for comparing mean values of outcomes before and after intervention in each study group.

**Resulted from ANCOVA for comparing two study groups based on mean values of outcomes after intervention and adjustment for baseline values.