Table 3.
Magnesium-supplemented group | Placebo group | Difference | |||||||
---|---|---|---|---|---|---|---|---|---|
Before | After | Mean difference ± SE | P value* | Before | After | Mean difference ± SE | P value* | P value** | |
SBP (mmHg) | 120.0 ± 20.1 | 115.7 ± 12.8 | − 4.2 ± 4.03 | 0.30 | 120.5 ± 13.3 | 113 ± 24.5 | − 7.5 ± 3.7 | 0.05 | 0.55 |
DBP (mmHg) | 76.8 ± 13.1 | 73.9 ± 9.2 | − 2. ± 3.2 | 0.38 | 79.2 ± 15.7 | 74.1 ± 13.0 | − 5.1 ± 3.2 | 0.12 | 0.98 |
Total-C (mg/dL) | 193.1 ± 37.5 | 188.2 ± 38.7 | − 4.9 ± 8.7 | 0.58 | 183.6 ± 40.8 | 176.9 ± 35.5 | − 6.7 ± 6.6 | 0.32 | 0.36 |
TG (mg/dL) | 156.4 ± 77.9 | 123.1 ± 48.4 | − 33.3 ± 14.0 | 0.02 | 158.0 ± 65.3 | 135.7 ± 51.7 | − 22.3 ± 8.9 | 0.01 | 0.28 |
HDL-C (mg/dL) | 46.0 ± 11.8 | 49.7 ± 10.9 | 3.7 ± 1.1 | 0.002 | 42.9 ± 7.8 | 43.6 ± 7.2 | 0.7 ± 0.7 | 0.29 | 0.003 |
LDL-C (mg/dL) | 99.9 ± 27.3 | 95.0 ± 24.1 | − 4.9 ± 5.3 | 0.37 | 97.7 ± 27.4 | 88.2 ± 22.2 | − 9.5 ± 4.2 | 0.03 | 0.25 |
HbA1c (%) | 5.8 ± 0.7 | 6.6 ± 0.8 | 0.8 ± 0.1 | < 0.001 | 5.8 ± 0.6 | 6.5 ± 0.8 | 0.7 ± 0.1 | < 0.001 | 0.55 |
FPG (mg/dL) | 115.1 ± 14.2 | 116.5 ± 13.7 | − 1.5 ± 2.0 | 0.48 | 112.5 ± 12.2 | 111.8 ± 14.3 | − 0.7 ± 1.8 | 0.72 | 0.29 |
FPI (μU/mL) | 8.2 ± 5.9 | 16.9 ± 7.8 | 8.7 ± 1.4 | < 0.001 | 14.8 ± 9.6 | 17.9 ± 8.4 | 3.2 ± 1.3 | 0.02 | 0.18 |
Uric acid (mg/dL) | 5.2 ± 1.4 | 4.9 ± 1.1 | − 0.2 ± 0.2 | 0.28 | 4.8 ± 1.1 | 5.1 ± 1.0 | 0.26 ± 0.1 | 0.04 | 0.09 |
CRP (mg/L) | 1.3 ± 2.7 | 3.1 ± 4.0 | 1.8 ± 0.5 | 0.001 | 1.3 ± 2.6 | 2.2 ± 2.1 | 0.8 ± 0.4 | 0.03 | 0.10 |
HOMA-IR index | 3.1 ± 4.4 | 4.9 ± 2.5 | 1.8 ± 0.9 | 0.06 | 4.0 ± 2.8 | 4.9 ± 2.6 | 0.9 ± 0.4 | 0.02 | 0.80 |
SBP systolic blood pressure, DBP diastolic blood pressure, C cholesterol, TG triglyceride, FPG fasting plasma glucose, fasting plasma insulin, CRP C-reactive protein.
*Resulted from paired t-test for comparing mean values of outcomes before and after intervention in each study group.
**Resulted from ANCOVA for comparing two study groups based on mean values of outcomes after intervention and adjustment for baseline values.